该文对肺炎衣原体感染与动脉粥样硬化的相关性、肺炎衣原体诱导的动脉粥样硬化病理改变及细胞因子在其中的作用进行了综述。肺炎衣原体可致呼吸系统疾病,通过慢性无症状感染,肺炎衣原体可通过肺部炎症进而扩展到动脉内膜,在一系列炎症因子和细胞因子作用下,可促进动脉粥样硬化的发生和病理改变。然而,肺炎衣原体感染所致动脉粥样硬化的确切机制尚不清楚。 This article reviews the relationship between Chlamydia pneumoniae infection and atherosclerosis, the pathological changes of atherosclerosis induced by Chlamydia pneumoniae and the role of cytokines in it. Chlamydia pneumoniae can cause respiratory diseases, through chronic asymptomatic infection, Chlamydia pneumoniae can be extended through the lung inflammation to the intima, a series of inflammatory cytokines and cytokines, can promote atherosclerosis and pathological changes . However, the exact mechanism of atherosclerosis due to Chlamydia pneumoniae infection is not clear.