为研究柯萨基B病毒性脑膜炎的流行特征和临床特点 ,采用病毒分离、酶联免疫吸附试验(ELISA)检测血清病毒抗体进行病原学检查 ,同时分析了患儿的症状、体征、实验室检查结果、治疗方法和预后。结果提示学龄前、学龄期儿童发病率高、病情轻、预后好。干扰素显示了明显的治疗效果。此次病毒性脑膜炎的流行由柯萨基B病毒引起 ,传播途径以消化道、呼吸道为主 ,干扰素治疗效果明显。 In order to study the epidemiological characteristics and clinical features of Coxsackie B virus meningitis, the virus isolates and enzyme-linked immunosorbent assay (ELISA) were used to detect the serum virus antibody for pathogenic examination. At the same time, the children’s symptoms and signs were analyzed. The laboratory Check the results, treatment and prognosis. The results suggest that pre-school, school-age children have high incidence, mild illness and good prognosis. Interferon shows a significant therapeutic effect. The epidemic of viral meningitis caused by the Coxsackie B virus, the main route of transmission to the digestive tract, respiratory tract, interferon treatment significantly.