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目的观察老年进展性脑梗死(PCI)患者的血清高敏C反应蛋白(hs-CRP)和同型半胱氨酸(Hcy)变化情况和对患者预后的影响。方法回顾性分析2010年2月至2012年8月收治的150例老年脑梗死患者的临床资料,其中PCI患者75例,探讨其血清hs-CRP和Hcy的变化情况。结果脑梗死组患者的血清Hcy和hs-CRP明显高于健康对照组,且PCI组患者的Hcy和hs-CRP也明显高于非PCI组患者。结论血清Hcy和hs-CRP水平检测有利于老年PCI患者的早期诊断,且对患者的预后具有一定的评估作用。
Objective To observe the changes of serum high-sensitivity C-reactive protein (hs-CRP) and homocysteine (Hcy) in elderly patients with progressive cerebral infarction (PCI) and its prognosis. Methods The clinical data of 150 elderly patients with cerebral infarction admitted to our hospital from February 2010 to August 2012 were retrospectively analyzed. Among them, 75 patients with PCI were enrolled in this study to investigate the changes of serum hs-CRP and Hcy. Results Serum Hcy and hs-CRP in patients with cerebral infarction were significantly higher than those in healthy controls, and Hcy and hs-CRP in patients with PCI were also significantly higher than those in non-PCI patients. Conclusion The detection of serum Hcy and hs-CRP levels is helpful for the early diagnosis of elderly patients with PCI, and has a certain evaluation on the prognosis of patients.