泮库溴铵类似物OrgNC45(2β,16β-二哌啶酮—3α,17β—二乙酰氧基—5α—雄甾烷)具有确切的肌松作用,家兔垂头剂量为19.35±2.7μg/kg,麻醉猫坐骨神经胫前肌阻断剂量为25μg/kg,作用持续38.4min。经典方法研究表明,它是一种非去极化肌松剂,起效时间为4.26±1.02min,恢复时间为3.02±1.02min,蓄积作用小,能使血压略有上升。对心血管系统无明显不良作用,是一较理想的肌松剂。 The pancuronium analogue OrgNC45 (2β, 16β-bipiperidone-3α, 17β-diacetoxy-5α-androstane) had the exact muscle relaxant effect with a rabbit head-down dose of 19.35 ± 2.7 μg / kg, anesthetized cat sciatic nerve tibialis anterior muscle block dose of 25μg / kg, the role of sustained 38.4min. The classical study shows that it is a kind of non-depolarizing muscle relaxants, the onset time is 4.26 ± 1.02min, the recovery time is 3.02 ± 1.02min, the accumulation of small, can make blood pressure rise slightly. No obvious adverse effects on the cardiovascular system, is an ideal muscle relaxant.