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目的对比分析非小细胞肺癌单纯手术与术后辅助放疗的临床疗效。方法收治非小细胞肺癌(Ⅱ及Ⅲa期)150例,随机分入两组(单纯手术组及术后放疗组),各组均75例,对其临床疗效予以观察对比。结果非小细胞肺癌(Ⅱ及Ⅲa期)术后放疗组与单纯手术组相比,局部控制率有显著提高(P<0.05);5年生存率及远处转移率两组相比差异无显著性(P>0.05)。结论非小细胞肺癌术后辅助放疗可降低局部复发率,但对5年生存率及远处转移率无明显影响;病理类型对其生存率亦无明显影响。
Objective To compare and analyze the clinical efficacy of simple surgery and postoperative adjuvant radiotherapy for non-small cell lung cancer. Methods 150 cases of non-small cell lung cancer (stage Ⅱa and Ⅲa) were enrolled and randomly divided into two groups (operation-only group and postoperative radiotherapy group), 75 cases in each group. The clinical curative effect was observed and compared. Results The local control rate of non-small cell lung cancer (Ⅱ and Ⅲa) postoperative radiotherapy group was significantly higher than that of the simple operation group (P <0.05). There was no significant difference in the 5-year survival rate and distant metastasis rate between the two groups (P> 0.05). Conclusions Postoperative adjuvant radiotherapy for non-small cell lung cancer can reduce the local recurrence rate, but has no significant effect on 5-year survival rate and distant metastasis rate. Pathological types have no significant effect on the survival rate.