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ｒａｓ基因族是人类实体肿瘤中最常见的癌基因，其编码的Ｐ２１蛋白过度表达促进细胞恶性转化，在一些肿瘤的发生发展中起作用［１］。用抗ｒａｓｐ２１单克隆抗体免疫组化双ＰＡＰ法，检测４３例鼻咽癌（ＮＰＣ）、４０例癌旁及１０例正常对照组的鼻咽部活体组织冰冻切片中
The ras gene family is the most common oncogene in human solid tumors. The overexpression of P21 protein promotes the malignant transformation of cells and plays a role in the development of some tumors [1]. The anti-rasp21 monoclonal antibody immunohistochemical double PAP method was used to detect nasopharyngeal carcinoma in 43 cases of nasopharyngeal carcinoma (NPC), 40 cases of paracancerous and 10 normal control group of nasopharyngeal biopsy frozen sections