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RNA干扰(RNA interference,RNAi)是利用具有同源性的双链RNA(double-stranded RNA,dsRNA)诱发序列特异的转录后基因沉默的现象。在进化上,可能是生物调控基因表达及抵御病毒入侵或转座子诱导DNA突变的一种共有的生理机制。目前在世界范围内,RNAi已经超过反义寡核苷酸和ribozyme
RNA interference (RNAi) is the phenomenon of using sequence-specific post-transcriptional gene silencing using double-stranded RNA (dsRNA) with homology. In evolution, it may be a common physiological mechanism for biological regulation of gene expression and resistance to virus invasion or transposon-induced DNA mutation. At present, RNAi has surpassed antisense oligonucleotides and ribozyme in the world