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作者在ICU中应用钢治团治疗中毒性休克、败血症、细菌性脑膜炎、一氧化碳中毒、脑梗死共104例,除细菌性脑膜炎病例数过少未作比较外,与对照组相比各指标均有显著性差异(P<0.05)。结果认为,1.纳洛酮在治疗严重感染性疾息时,通过结抗体内β-内啡肽,稳定细胞微粒体膜阻止其酶的释放而发挥抗炎作用;2.纳洛酮具有催醒和促进神经系统病变恢复的作用;3.纳洛酮具有高效抗休克作用,特别是感染性休克。
The author in the ICU application of steel treatment group of toxic shock, sepsis, bacterial meningitis, carbon monoxide poisoning, cerebral infarction, a total of 104 cases, in addition to the number of bacterial meningitis is not too small, compared with the control group indicators There was significant difference (P <0.05). The result is that, 1. Naloxone exerts anti-inflammatory effect by inhibiting the release of beta-endorphin in vivo and stabilizing the cellular microsomal membrane in the treatment of severe infectious diseases. Naloxone can arouse and promote the recovery of nervous system diseases; 3. Naloxone has an effective anti-shock effect, especially septic shock.