曼氏血吸虫具有一种5-羟色胺激活的腺苷酸环化酶(AC)。在尾蚴发育为成虫的过程中,此酶的活性大大增加。AC 系统有3个主要成份:结合激素激活剂(5-羟色胺)的受体;催化由 ATP 合成 cAMP 的催化组分;以及涉及信号从受体传导到催化部位的 GTP Schistosoma mansoni has a serotonin-activated adenylate cyclase (AC). During the development of cercariae into adults, the activity of this enzyme is greatly increased. The AC system has three main components: a receptor that binds a hormone activator (serotonin); a catalytic component that catalyzes the synthesis of cAMP from ATP; and a GTP that involves signaling from the receptor to the catalytic site