Bristol于1962年首先提出小肠恶性肿瘤可能合并有麦胶性肠病(Coeliac disease)。以后的报告证实特别是上、中消化道癌肿常伴有麦胶性肠病。Birminaham的研究指出,麦胶性肠病的病人可能发生恶性肿瘤者高达14%,恶性肿瘤中大约一半是淋巴瘤。淋巴瘤的组织学类型大多是何杰金氏病或网状细胞肉瘤,近来有人指出应归属于恶性组织细胞增多病。在235例(其中男122,女113)麦胶性肠病合并恶性肿瘤的病人中,诊断为麦胶性肠病的平均年龄为 In 1962, Bristol first proposed that malignant tumors of the small intestine may be associated with Coeliac disease. Later reports confirmed that especially upper and middle digestive tract cancers are often accompanied by MG. According to Birminaham’s study, up to 14% of patients with malignancy can develop malignancy, and about half of malignancy is lymphoma. The histological type of lymphoma is mostly Hodgkin’s disease or reticular cell sarcoma, and it has recently been pointed out that it belongs to malignant histiocytosis. In 235 patients (122 males and 113 females) with malignancy associated with malignancy, the average age of diagnosis of maltooligosis was