本文对17例肝癌患者行20次肝动脉化疗栓塞(TACE)后上消化道粘膜损害的发生率和内镜下特征进行初步探讨。TACE后有12例次出现新的上消化道粘膜损害或原病损加剧占60％,损害部位自食道至十二指肠降部,粘膜呈弥漫性或局灶性。粘膜损害呈不规则充血、水肿、糜烂和粘膜下出血灶。分析其损害原因可能与栓塞物质造成粘膜缺血、抗癌药物毒性作用和应激反应有关,鉴此,在行TACE术前建议应常规做胃镜检查。 In this paper, the incidence and endoscopic features of upper gastrointestinal mucosa in 20 patients with hepatocellular carcinoma after TACE were studied. TACE after 12 cases of new upper gastrointestinal mucosal damage or the original lesion exacerbated 60% damage from esophageal to duodenal descending, mucosal diffuse or focal. Mucosal damage was irregular congestion, edema, erosion and submucosal hemorrhage. Analysis of the causes of damage may be caused by embolic material caused by mucosal ischemia, toxic effects of anti-cancer drugs and stress response, therefore, in line TACE preoperative recommendations should be routine gastroscopy.