糖尿病是一常见病和多发病。虽然由于胰岛素的广泛应用,已使它的严重后果大为改观,但并没有解决糖尿病的慢性并发症对健康和生命的威胁。由电脑调控的超小型植入性人工胰腺和胰岛移植的研究,虽已取得一些进展,但离实用为时尚远。近年来对调节生长激素、胰高血糖素和胰岛素等多种激素分泌的生长抑制素(somatostatin,SS)的分离、鉴定和人工合成成功,为糖尿病的治疗研究开辟了新的途径。不少研究者已在这方面进行了很多有益的探索,本文摘要予以介绍。关于SS的基础研究 SS是在1972年首先由Guillemin等人从羊的下丘脑提纯的一种多肽激素。由于它对生长 Diabetes is a common disease and frequently-occurring disease. Although its serious consequences have been greatly improved due to the widespread use of insulin, it does not address the health and life-threatening consequences of the chronic complications of diabetes. Computer-controlled ultra-miniature implantable artificial pancreas and islet transplantation research, although some progress has been made, but far from practical. In recent years, the isolation, identification and synthesis of somatostatin (SS), which regulate the secretion of somatotropin, glucagon and insulin, have opened up new avenues for the treatment of diabetes. Many researchers have done a lot of useful exploration in this aspect, and the abstract of this article is introduced. Basic Research on SS SS is a polypeptide hormone that was first purified from the hypothalamus of sheep in 1972 by Guillemin et al. Because of its growth