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在不明原因不育病人中约有10%有抗精子抗体。本文应用微量滴定滤器放射免疫技术测定血浆标本中,对精子具有特异性的免疫球蛋白G(IgG)。并对388例不明原因不育病人作了检测,其结果阳性者为38/388(9.79%)。其中妇女阳性者为18/205(8.78%),男性阳性者为20/183(10.93%)。夫妇双方都为阳性者为4/123(3.25%)。测定血浆抗精子抗体的微量滴定滤器技术与其他放射标记抗球蛋白技术有高度相关性。作者在应用这种方法检测的同时,将同份标本再送另一实验室,用其他方法进行测定。结论二种方法为相同的结果。研究结果表明,阳性结果的发生率在不育症中约占10%。在男性和女性中阳性率的分布相等。
About 10% of unexplained infertility patients have anti-sperm antibodies. In this paper, microtiter filter radioimmunoassay was used to determine the immunoglobulin G (IgG) specific to sperm in plasma samples. And 388 cases of unexplained infertility were tested, the result was positive 38/388 (9.79%). Among them, women were 18/205 (8.78%) positive and 20/183 (10.93%) were male. The number of couples who were both positive was 4/123 (3.25%). The microtitre filter technique for measuring plasma anti-sperm antibodies is highly correlated with other radiolabeled antiglobulin technologies. The authors apply this method of testing at the same time, the same specimen sent to another laboratory, measured by other methods. Conclusion The two methods are the same result. The results show that the incidence of positive results in infertility accounts for about 10%. The distribution of positive rates is equal in both men and women.