洋地黄的有效治疗量与中毒量非常接近,故易发生过量或中毒,这已为临床医生所熟知。但用维持量之洋地黄,特别是用毒性低、排泄较快的地高辛,也可在某种情况下发生中毒,尚未引起临床医生的重视。本文对22例在用维持量地高辛过程中发生中毒的病例作以分析。分析的对象与方法全部病例均为住院患者,为治疗心衰或/和控制室上性心律失常所致的快速性室率而用洋地黄,洋地黄化后用维持量地高辛0.125～0.25mg/日.在此期间若发生下列情况,即认为地高辛中毒:①出现新的心律失常或原有心律失常加重。②停用地 Digitalis effective treatment and the amount of poisoning is very close, it is prone to excessive or poisoning, which is already well known to clinicians. But to maintain the amount of digitalis, especially with low toxicity, faster excretion of digoxin, but also in some cases poisoning has not attracted the attention of clinicians. In this article, 22 cases of poisoning during maintenance digoxin were analyzed. Subjects and Methods of Analysis All cases were hospitalized and treated with digitalis for the treatment of heart failure or / and rapid ventricular arrhythmias due to supraventricular arrhythmias, with digitalis maintained with digoxin 0.125-0.25 mg / day. In the meantime, digoxin poisoning should be considered as follows: ① new arrhythmia or aggravating arrhythmia. ② deactivated