地高辛治疗指数较小。用放射免疫法测定血浆地高辛浓度,可确定治疗剂量的范围和更准确地估计个体的需要量。在大多数心房纤颤患者,用于控制心率所需地高辛浓度为1.0—2.5毫微克分子/升。通过血浆地高辛浓度的测定,可了解它的吸收限度以及与其它药物的相互作用。现代地高辛制剂溶解迅速,因而与胃复安和抗胆硷能药物的相互作用没有明显的临床重要性。 Digoxin treatment index smaller. Using radioimmunoassay to measure plasma digoxin concentrations, the range of therapeutic doses can be determined and the individual’s needs estimated more accurately. In most patients with atrial fibrillation, the digoxin concentration required to control heart rate is 1.0-2.5 ng / ml. By measuring plasma digoxin concentration, you can see its absorption limit and the interaction with other drugs. Modern digoxin preparations dissolve rapidly, and therefore the interaction with metoclopramide and anticholinergic drugs has no obvious clinical significance.