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青少年的成人起病型糖尿病(MODY,也称么),进入人们的视野几乎已一个世纪。最早对“MODY”做过描述的是1928年Cammidge等~[1];正式采用MODY命名来描写这组显性常染色体家族遗传性疾病的是Tattersall和Fajans二位在1935年~[2]。至今还依然延续着,1998年Heffersley等~[3]建议的英国和法国在遗传研究中使用的标准,作为今天认识MODY的诊断标准。直到2005年在Joslin糖尿病学第14版书中记载着,仅MODY 1~5亚型,(1)HNF4A编码肝
Adolescent adult onset type diabetes (MODY, also known as), into people’s vision for almost a century. The earliest description of “MODY” was made by Cammidge et al. [1928] [1]. The formal use of MODY nomenclature to describe this group of dominant autosomal familial diseases is that Tattersall and Fajans, two in 1935 ~ [2 ]. To date, the criteria used in genetic studies by Britain and France recommended by Heffersley et al. [3] in 1998 are still valid as diagnostic criteria for MODY today. Until 2005 in the Joslin Diabetes 14th edition of the book, only MODY 1 ~ 5 subtypes, (1) HNF4A encoding liver