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为探讨延长AMI后存活者的寿命,由莱州市12家医院协作对1988年1月至1991年1月住院的AMI421例,按住院的顺序随机分成4组。A、B、C组分别长期口服心得安、卡托普利、心得安加卡托普利,D组为对照,进行1年的前瞻性观察,结果显示:A组与C组的猝死发生率均较低,但与D组相比无显著性差异。B组的左心衰竭发生率、C组的总死亡率均比D组显著降低(P<0.05)。B组总死亡率,虽比D组低,但无显著性差异。文内对这些疗效的作用机理进行了初步的探讨。
In order to explore the life span of survivors after prolonging AMI, 421 cases of AMI hospitalized by 12 hospitals in Laizhou City from January 1988 to January 1991 were randomly divided into 4 groups according to the order of hospitalization. A, B, C were long-term oral propranolol, captopril, experience and capsaicin, D group as a control, a one-year prospective observation, the results showed: A and C group of sudden death rate Lower, but no significant difference compared with the D group. The incidence of left heart failure and total mortality in group C were significantly lower than those in group D (P <0.05). Total mortality in group B, although lower than in group D, was not significantly different. The text of the mechanism of action of these effects were initially explored.