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目的:探讨鼻咽纤维内镜在鼻腔的导入是否可引起腭裂患者鼻音化率值的改变，验证鼻咽纤维内镜与鼻音计同步检查腭裂患者腭咽闭合状态的可行性。方法:纳入2004年8月至2010年8月北京大学口腔医学院·口腔医院口腔颌面外科收治的33例腭裂住院患者，男性24例，女性9例，平均年龄为15.3岁，比较鼻音计单独检查、鼻音计与鼻咽纤维内镜同步检查两种检查状态下患者的33个语音样本的鼻音化率值，进行配对n t检验并统计分析。n 结果:33例腭裂患者在鼻音计单独检查、鼻音计与鼻咽纤维内镜同步检查两种状态下，33个语音样本的鼻音化率值均值差异均无统计学意义（n P>0.05）。n 结论:鼻音计与鼻咽纤维内镜可进行同步检查腭裂患者腭咽闭合功能，鼻咽纤维内镜定性评价腭咽闭合功能的同时得到的鼻音化率值是准确可靠的，为进一步采集不同腭咽闭合状态下鼻音化率值提供了方法学基础。“,”Objective:To evaluate the changes of nasalance when cleft palate patients examined using nasometer and nasopharyngeal fiberscopy simultaneously.Methods:A total of 33 cleft palate patients from August 2004 to August 2010 were examined by nasopharyngeal fiber endoscopy and nasometer simultaneously. The nasalance of 33 voice samples was compared under two situations only nasometer and nasometer with nasopharyngeal fiberscopy.Results:The statistics showed that the nasalance value of 33 voice samples of 33 participants under different situations were no significant difference through paired n t-test (n P>0.05).n Conclusions:Nasopharyn fiber endoscopy had no influence to the results of the nasalance value under simultaneous condition. The nasometer and nasopharyn fiber endoscopy can be applied to evaluate the velopharyngeal function of cleft palate patients simultaneously.