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目的 探讨急性时相蛋白 (APP)与脑卒中预后的关系。方法 对116例脑卒中患者在发病3天内检测血清APP水平 ,分析其与临床转归的关系。结果 70例血清APP水平正常患者的临床好转率 (92.9% )明显高于46例APP水平升高患者 (26.1% ,χ2=44.85,P<0.01) ,而并发症的发生率 (5.71% )则明显低于后者 (63.04% ,χ2=46.33,P<0.01)。血清APP水平与治疗后神经功能缺损评分的减少值呈显著负相关 (P<0.05或<0.01)。结论 血清APP水平与患者的预后及并发症的发生有关
Objective To investigate the relationship between acute phase protein (APP) and stroke prognosis. Methods One hundred and sixteen patients with stroke were tested for serum APP level within 3 days after onset, and their relationship with clinical outcome was analyzed. Results The clinical improvement rate (92.9%) in 70 patients with normal serum APP level was significantly higher than that in 46 patients with elevated APP level (26.1%, χ2 = 44.85, P <0.01), while the incidence of complications was 5.71% Significantly lower than the latter (63.04%, χ2 = 46.33, P <0.01). The level of serum APP was negatively correlated with the reduction of neurological deficit score after treatment (P <0.05 or <0.01). Conclusion The serum level of APP correlates with the prognosis and complications of the patients