采用响应面分析法优化雷丸多糖的提取工艺。采用单因素实验选取实验因素与水平。根据Central Composites实验设计原理,采用4因素3水平的响应面分析法。在分析各因素显著性及其交互作用的基础上,得出雷丸多糖的最佳提取工艺条件,即提取温度100℃,料液比1∶21,提取时间93min,提取2次,测得的雷丸多糖得率为23.12%。 Response surface analysis was used to optimize the extraction process of Lei pill polysaccharide. Single factor experiments were used to select experimental factors and levels. According to the Central Composites experimental design principle, a 4 factor 3 level response surface analysis method was used. On the basis of analyzing the significance of each factor and its interaction, the optimum extraction process conditions of Lei Pang polysaccharide were obtained, namely the extraction temperature 100°C, the ratio of solid to liquid 1:21, the extraction time 93min, and extraction 2 times. Ray pill polysaccharide yield was 23.12%.