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目的探讨纳洛酮联合醒脑静治疗急性酒精中毒的临床疗效。方法 70例急性酒精中毒患者,随机分为治疗组和对照组,各35例。在洗胃和相关对症支持治疗的基础上,治疗组用纳洛酮联合醒脑静治疗,对照组单用纳洛酮治疗。观察两组意识恢复时间及症状改善时间。结果治疗组的意识恢复时间为(2.85±0.67)h、症状改善时间为(6.78±0.82)h,对照组的意识恢复时间为(3.48±0.36)h、症状改善时间为(8.26±0.68)h,比较差异均有统计学意义(P<0.05)。治疗组总有效率为97.1%;对照组总有效率为77.1%;比较差异具有统计学意义(P<0.05)。结论纳洛酮联合醒脑静治疗酒精中毒患者的临床疗效显著,值得广大急诊工作者和基层医疗单位推广应用。
Objective To investigate the clinical efficacy of naloxone combined with xingnaojing in the treatment of acute alcoholism. Methods Seventy patients with acute alcoholism were randomly divided into treatment group and control group, 35 cases each. On the basis of gastric lavage and related symptomatic supportive therapy, the treatment group was treated with naloxone combined with xingnaojing and the control group with naloxone alone. Observe the recovery time and symptom improvement time of two groups. Results The recovery time was (2.85 ± 0.67) h in the treatment group, (6.78 ± 0.82) h in the control group, (3.48 ± 0.36) h in the control group, and (8.26 ± 0.68) h in the control group , The difference was statistically significant (P <0.05). The total effective rate of the treatment group was 97.1%; the total effective rate of the control group was 77.1%; the difference was statistically significant (P <0.05). Conclusion Naloxone combined with Xingnaojing has significant clinical efficacy in the treatment of patients with alcoholism, and it is worthy of promotion and application by the vast number of emergency workers and primary medical units.