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目的分析醒脑静注射液对急性酒精中毒患者氧代谢及氧化应激的影响。方法 120例急性酒精中毒患者,随机分为对照组和观察组,各60例。对照组患者给予常规基础治疗,观察组患者在给予常规基础治疗基础上增加醒脑静注射液静脉滴注治疗。分析比较两组患者氧代谢及氧化应激相关指标的差异。结果治疗后4 h,观察组的血氧饱和度、动脉血氧含量、氧合指数分别为(93.29±9.86)%、(153.86±11.12)mmol/dl、(230.14±22.21),均显著优于对照组的(83.28±9.91)%、(123.45±9.69)mmol/dl、(204.65±21.13)(P<0.05)。结论醒脑静注射液有利于急性酒精中毒患者的氧代谢及氧化应激情况,有较好的临床效果,值得临床借鉴。
Objective To analyze the effects of xingnaojing injection on oxygen metabolism and oxidative stress in patients with acute alcoholism. Methods 120 patients with acute alcoholism were randomly divided into control group and observation group, with 60 cases in each. Patients in the control group were given routine basic treatment. Patients in the observation group were given intravenous infusion of Xingnaojing injection on the basis of routine basic treatment. Analysis and comparison of oxygen metabolism and oxidative stress differences between two groups of patients. Results The blood oxygen saturation, arterial oxygen content and oxygenation index of the observation group were (93.29 ± 9.86)% and (153.86 ± 11.12) mmol / dl and (230.14 ± 22.21) 4 h after the treatment, respectively, The control group (83.28 ± 9.91)%, (123.45 ± 9.69) mmol / dl, (204.65 ± 21.13) (P <0.05). Conclusion Xingnaojing injection is good for oxygen metabolism and oxidative stress in patients with acute alcoholism, and has good clinical results, which is worthy of clinical reference.