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目的:观察大蒜素对离体肾内动脉经血管收缩剂预收缩张力的影响,探讨其作用机制。方法:显微操作下取SD大鼠肾内动脉,制备成1.8～2.0 mm长的血管条,用2根不锈钢丝穿过血管腔,固定于微血管测定仪的浴槽内。分别给予血管收缩剂
Objective: To observe the effect of allicin on the premature contraction of isolated renal artery vasoconstrictors and to explore its mechanism. METHODS: SD rats were subjected to intrarenal arterial micromanipulation under microsurgery to prepare vascular strips of 1.8-2.0 mm in length. Two stainless steel wires were inserted through the vascular lumen and fixed in the bath of the microvascular analyzer. Vasoconstrictors were given