IgA肾病（IgANP）是我国最常见的肾病之一。主要表现为肾小球系膜区大量IgA沉积，系膜细胞增生及基质增多。病情迁延，预后较差，其病因及发病机制尚不清楚。Nmp等［1］及Im等［2］报道IgANP，患者血清HBSAg阳性率分别为15．6％和17．3％，明显高于当地正常人群（0．99％，9．5 IgA nephropathy (IgANP) is one of the most common kidney diseases in China. Mainly as a large number of glomerular mesangial IgA deposition, mesangial cell proliferation and matrix increased. Prolonged disease, the prognosis is poor, its etiology and pathogenesis is unclear. Nmp et al [1] and Im et al [2] reported IgANP, the positive rate of serum HBsAg was 15.6% and 17.3%, significantly higher than the local normal population (0.99%, 9.5