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一、前言使用HMG诱发排卵,从1960年由Lunenfeld应用于临床以来,广泛地认为对第二度闭经及用Clomiphene无效的第一度闭经有效。作者对156例妇女用HMG-HCG诱发排卵,排卵率为64.1%,妊娠率为35.9%。使用本疗法常见的副作用有:卵巢过度刺激症候群、多胎妊娠、高流产率等,目前尚无很好的解决方法。如包括轻度卵巢过度刺激症候群则在多数排卵病例中均可见到本症、在妊娠病例中发生率更高,且可有重症,也有多胎妊娠与高流产率,故须考虑本疗法的副作用。副作用的狭义意义,只是指卵巢过度刺激症候群。本文对其发生情况及对策进行叙述。
I. INTRODUCTION The use of HMG to induce ovulation has been widely recognized as effective for the first time since menopause and for the first time with Clomiphene being ineffective since Lunenfeld’s application to the clinic in 1960. The author of 156 cases of women with ovulation induced by HMG-HCG, ovulation rate was 64.1%, the pregnancy rate was 35.9%. Common side effects of the use of this therapy are: ovarian hyperstimulation syndrome, multiple pregnancies, high abortion rate, there is no good solution. Such as mild ovarian hyperstimulation syndrome in the majority of cases of ovulation can be seen in this disease, the incidence of pregnancy is higher, and may have severe, there are multiple pregnancies and high abortion rates, it is necessary to consider the side effects of this therapy. The narrow sense of side effects, but refers to ovarian hyperstimulation syndrome. This article describes the situation and countermeasures.