近年研究发现,在正常和病变的心脏组织中都有染色体有丝分裂象和胞质的分裂,并出现了分裂前后细胞表面标志物的变化,这说明心脏组织内有些细胞具有更新和分化能力。能够在心脏组织中发挥修复作用的细胞有两种来源,一是外源性的干细胞通过血液在心脏定植转分化为心肌组织;另一个是内源性心脏干细胞(endogenous cardiac stem cells,ECSC),在促分化因素作用下进入细胞分裂循环。本文主要讨论ECSC研究的进展。 Recent studies have found that in both normal and diseased heart tissue, there are chromosome mitosis and cytoplasmic division and changes in cell surface markers before and after division, indicating that some cells in the heart tissue are capable of renewing and differentiating. There are two sources of cells capable of exerting a repair function in heart tissue. One is that exogenous stem cells are transplanted into cardiac tissue by blood transplanting in heart; the other is endogenous cardiac stem cells (ECSC) Promote differentiation in the role of cell division cycle. This article focuses on the progress of ECSC research.