By doping Ni into YBa2Fe3O8+w (YBFO) system,we obtained the phase YBa2Fe3-xNixO8+w (YBFNO,x=0,0.05,0.10,0.15,0.30,0.50,1.00).This paper discusses the changes in crystal structural,resistivity and magnetoresistivity (MR) of YBFO samples due to the incorporation of transition metal Ni.The results show that Ni substitution for partial Fe in YBFO does not substantially transform the structure of parent phase,but results in tiny changes in the lattice parameters.The YBFO crystal with Ni doped is semiconducting.