为探讨腺上皮起源的涎腺良、恶性肿瘤与人乳头瘤病毒（Ｈｕｍ ａｎ ｐａｐｉｌｌｏｍ ａｖｉｒｕｓ， ＨＰＶ）感染的关系，应用聚合酶链反应技术（ＰＣＲ），采用共有引物检测４４例涎腺肿瘤组织中的ＨＰＶ ＤＮＡ的存在状况。１０ 例正常涎腺组织作为对照。结果显示：肿瘤组织中ＨＰＶ ＤＮＡ 阳性检出率达７０．４５％ （３１／４４），其中恶性肿瘤 ＨＰＶＤＮＡ 阳性率为７７２７％ （３１／４４）；良性肿瘤ＨＰＶＤＮＡ阳性率为６３６３％ （１４／２２）；而正常对照组织中ＨＰＶ ＤＮＡ阳性率仅为１０％ （１／１０）。提示：涎腺肿瘤的发生可能与ＨＰＶ感染有关 In order to explore the relationship between adenoid and gonadal carcinomatous and human papillomavirus (HPV) infection, we use polymerase chain reaction (PCR) to detect 44 cases of salivary gland tumors The presence of HPV DNA in the tissue. Ten cases of normal salivary gland tissue as a control. The results showed that the positive rate of HPV DNA in tumor tissue was 70.45% (31/44), the positive rate of HPVDNA in malignant tumor was 7727% (31/44), and the positive rate of HPV DNA in benign tumor was 6363% (14/22), while the HPV DNA positive rate in normal control tissues was only 10% (1/10). Tip: salivary gland tumors may be related to HPV infection