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目的:探讨左氧氟沙星所致不良反应(ADR)的情况,为临床用药提供帮助,以指导临床合理用药。方法:收集使用左氧氟沙星发生药物不良反应39例病例进行统计分析。结果:发生不良反应的39例中,首次使用即发生症状者30例(76.92%),连续用药2次以上才发生ADR的9例(23.78%)。症状最早出现者为首次使用后5s,最迟时间发生在首次用药后1天。男性发生ADR16例(41.03%),女性发生ADR23例(58.97%)。口服发生8例(20.51%),静脉给药发生31例(79.49%)。结论:临床用药中应注意左氧氟沙星的不良反应,尽量给予口服治疗,早发现,及时处理。
Objective: To investigate the adverse reactions caused by levofloxacin (ADR), to provide help for clinical medication to guide clinical rational use of drugs. Methods: A total of 39 cases of adverse drug reactions using levofloxacin were collected for statistical analysis. Results: Of the 39 cases with adverse reactions, 30 cases (76.92%) were those who had symptoms for the first time, and 9 cases (23.78%) had ADR occurred more than 2 times. Symptoms first appeared 5s after the first use, the latest time occurred after the first day of treatment. There were 16 cases of ADR in men (41.03%) and 23 cases of ADR in women (58.97%). Oral 8 cases (20.51%), intravenous administration occurred in 31 cases (79.49%). Conclusion: The clinical medication should pay attention to the adverse reactions of levofloxacin, try to give oral treatment, early detection and timely treatment.