目的探讨靶向血管治疗脑胶质瘤的研究进展。方法分别从该方法的依据、具体方法、肿瘤血管抑制剂的开发、抗血管基因治疗、优越性以及存在问题与展望等方面对靶向血管治疗脑胶质瘤这一策略进行回顾总结。结果靶向血管治疗脑胶质瘤方法可行,前景诱人。结论随着分子生物学的发展,肿瘤血管抑制剂的不断开发和研究,对于脑胶质瘤这一血管增生极为突出的肿瘤,深入研究抗血管治疗具有重要意义。 Objective To investigate the progress of targeted vascular treatment of glioma. Methods The strategies of targeting vascular treatment of glioma were reviewed respectively based on the basis of the method, the specific method, the development of tumor vasoconstrictors, the anti-vascular gene therapy, advantages and the existing problems and prospects. Results Targeted vascular treatment of glioma feasible, attractive prospects. Conclusion With the development of molecular biology, the continuous development and research of tumor angiogenesis inhibitors has great significance for the study of glioma, an extremely prominent tumor of vascular proliferation and further study of anti-angiogenic therapy.