论文部分内容阅读
目的探讨诊断视神经炎的有效MRI检查序列以及MRI与VEP的相关性。设计回顾性病例系列。研究对象55例(110眼)出院诊断视神经炎、视神经乳头炎、多发性硬化、视神经脊髓炎的视力下降患者。方法对上述患者行常规颅脑MRI、视神经STIR和Gd-DTPA增强扫描联合脂肪抑制技术,分析MRI图像,对MRI和VEP结果与临床视力表现的一致性进行分析;对MRI与VEP的一致性进行分析。主要指标视力,MRI视神经信号、形态、强化,视觉诱发电位P_(100)潜伏期。结果视力与MRI之间的一致性为81.81%,Kappa(κ)值为0.500。视力与VEP之间的一致性为86.32%,κ=0.581。MRI表现与VEP结果之间存在一定的一致性,κ=0.378。结论MRI脂肪抑制技术和Gd-DTPA增强扫描联合脂肪抑制技术有助于视神经炎定位和定性诊断,VEP有助于视神经炎的诊断和亚临床病灶发现。MRI结合VEP能提高诊断的准确率。(眼科,2007,16:319-322)
Objective To explore the effective MRI examination sequence for diagnosis of optic neuritis and the correlation between MRI and VEP. Design retrospective case series. Subjects 55 patients (110 eyes) discharged diagnosed optic neuritis, optic nerve head inflammation, multiple sclerosis, optic neuromyelitis in patients with decreased vision. Methods The above patients underwent routine craniocerebral MRI, optic nerve STIR and Gd-DTPA enhanced scans combined with fat suppression technique to analyze MRI images and analyze the consistency of MRI and VEP results with clinical visual acuity. The consistency between MRI and VEP analysis. Main indicators of visual acuity, MRI optic nerve signal, morphology, enhancement, visual evoked potential P_ (100) latency. Results Consistency between visual acuity and MRI was 81.81%, Kappa (κ) value was 0.500. Consistency between visual acuity and VEP was 86.32%, κ = 0.581. There was some consistency between MRI findings and VEP results, κ = 0.378. Conclusions MRI fat suppression and Gd-DTPA combined with fat suppression technique may be helpful for the localization and qualitative diagnosis of optic neuritis. VEP may contribute to the diagnosis of optic neuritis and the detection of subclinical lesions. MRI combined with VEP can improve the diagnostic accuracy. (Ophthalmology, 2007, 16: 319-322)