目的探讨早补救ICSI患者精液参数的分布规律,从而为有效选择受精方式提供实验室依据。方法回顾分析早补救ICSI的患者189例和IVF受精的患者446例,对比两组患者不同精液参数的分布情况。结果 R-ICSI组患者不同程度精子数量、活力的分布与IVF组相比存在明显差异(P<0.05)。R-ICSI组少精子症、弱精子症的比例明显高于IVF组,而精子数量正常、精子活力正常的比例明显低于IVF组。R-ICSI组少精子症且同时存在弱精子症的比例明显高于IVF组。R-ICSI组患者不同程度精子形态的分布与IVF组相比无明显差异(P>0.05)。结论遇到精子参数异常的情况,尤其是在精子数量和活力同时出现异常时,提示患者可能存在受精障碍,应行早去颗粒细胞以便观察第二极体的出现。有针对性地实行早补救ICSI,就可以在不扩大ICSI指征的同时,又避免受精失败的发生。 Objective To investigate the distribution of sperm parameters in patients with ICSI as early recovery, so as to provide a laboratory basis for effective selection of fertilization methods. Methods A total of 189 ICSI patients and 446 IVF fertilized patients were retrospectively analyzed. The distribution of different semen parameters in two groups were compared. Results The distribution of sperm count and vitality of R-ICSI patients were significantly different from those of IVF patients (P <0.05). R-ICSI group of oligozoospermia, asthenospermia was significantly higher than the proportion of IVF group, while the number of normal sperm, normal sperm motility was significantly lower than the proportion of IVF group. R-ICSI oligozoospermia and the presence of asthenospermia was significantly higher than the proportion of IVF group. There was no significant difference in the distribution of sperm morphology between R-ICSI patients and IVF patients (P> 0.05). Conclusion In the case of abnormal sperm parameters, especially in the case of simultaneous abnormalities of sperm count and vitality, it suggests that there may be impaired fertilization and should go to granulocyte as early as possible to observe the appearance of the second polar body. Targeted implementation of early recovery ICSI, we can not expand the ICSI indications, but also to avoid fertilization failure.