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应用小鼠S1 80 肉瘤 ,小鼠EAC腹水瘤实体型两种瘤株 ,进行BALB c小鼠移植瘤模型的研究。试验设S1 80 对照组 ,S1 80 给药组 ,EAC对照组 ,EAC给药组 ,比较给药 10d后实体瘤大小及其病理学变化特征。病理学观察对照组和给药组间、瘤体切面积和瘤细胞坏死率差异均有极显著性 ,两对照组的小鼠肝脏内均发现有瘤细胞转移。由此说明病理学观察具有重要的参考价值
The mouse S180 sarcoma and mouse EAC ascites tumor were used to study the tumor model of BALB / c mice. S180 control group, S180 administration group, EAC control group and EAC administration group were set up to compare the size and pathological changes of solid tumors after administration for 10 days. Pathological observation between the control group and the administration group, the tumor area and tumor necrosis rate were significantly different, both control mice liver tumor cells were found to have metastasized. This shows that the pathological observation has important reference value