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作者介绍了五年期间用碘标记MIBG显像检查16例神经母细胞瘤患儿的经验.患者年龄为1周～12岁(半数在3岁以下),15例在诊断时尿儿茶酚胺含量高于正常.~(131)I-MI-BG剂量为18.5MBq(0.5mCi),静脉注射后48小时显像.~(123)I-MIBG剂量为74MBq(2mCi),注射后24小时显像.注射前患者均口服碘剂以封闭甲状腺.部分病人加做~(99m)Tc-DTPA肾显像或~(99m)Tc-胶体肝脾显像以协助定位,加做~(99m)Tc-MDP显像诊断骨转移.
The authors introduced the experience of using iodine-labeled MIBG imaging to examine 16 children with neuroblastoma over a five-year period. The patient’s age ranged from 1 week to 12 years (half of the patients were under 3 years of age). The urinary catecholamine content was higher in 15 patients at the time of diagnosis. Normal ~(131)I-MI-BG dose was 18.5 MBq (0.5 mCi), 48 hours after intravenous injection. ~(123)I-MIBG dose was 74 MBq (2 mCi), 24 hours after injection. All patients received oral iodine to block the thyroid gland. Some patients were treated with ~(99m)Tc-DTPA renal imaging or ~(99m)Tc-colloidal hepatosplenic scintigraphy to aid localization, and ~(99m)Tc-MDP was added. Like diagnose bone metastases.