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目的:探讨盐酸屈他维林、三莨菪碱在促进产程中的作用。方法:取2010年01月至2010年06月期间在我院分娩的初产妇随机分为屈他维林治疗组,三莨菪碱治疗组及对照组各50例。治疗组分别予盐酸屈他为林40mg,山莨菪碱10mg静脉推注,对照组不推注任何药物,观察各组的产程进展情况及对母婴安全的影响。结果:屈他维林与山莨菪碱组在产程、剖宫产上无显著性差异(P>0.05),屈他维林组、山莨菪碱组与对照组在第一产程上明显缩短,有显著差异性(P<0.05),屈他为林组、山莨菪碱组与对照组间剖宫产率差异具有显著(P<0.05),产后出血率、新生儿窒息率屈他为林组、山莨菪碱组与对照组间差异无显著性(P>0.05),屈他为林组与山莨菪碱组间不良反应差异具有显著性(P<0.05)。结论:应用屈他维林可达到与山莨菪碱一样的促进第一产程进展的作用,且不良反应少,可考虑使用。
Objective: To investigate the role of triptorelin hydrochloride and scopolamine in promoting labor. Methods: The primipara which was delivered in our hospital from January 2010 to June 2010 were randomly divided into three groups: metatline treatment group, scopolamine treatment group and control group. The treatment group were given Qu Yuan Lin 40mg, Anisodamine 10mg intravenous injection, the control group did not push any drugs to observe the progress of labor in each group and the impact on maternal and child safety. Results: There was no significant difference between labor group and cesarean section in the group of triptorelin and anisodamine (P> 0.05). The rates of the first trimester of triptorelin, anisodamine and control group were significantly shortened (P <0.05). There was a significant difference in the rate of cesarean section among them (P <0.05), postpartum hemorrhage rate and neonatal asphyxia rate in Quota group, anisodamine group and control group There was no significant difference between anisodamine group and control group (P> 0.05). There was a significant difference between the anisodamine group and anisodamine group (P <0.05). CONCLUSION: The use of trootavirin can achieve the same effect as anisodamine in promoting the progress of the first stage of labor with less adverse reactions and can be considered for use.