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Ｌｅｂｅｒ遗传性视神经病 (ＬＨＯＮ)是一种主要累及黄斑束纤维 ,导致视神经退性变的线粒体性遗传病。本病由ｖｏｎＧｒａｅｆｅ(1 85 8)最早报道 ,1 871年Ｌｅｂｅｒ’ｓ收集了 1 6个家庭中 5 5例 ,并明确为一种独立的遗传性疾病。Ｅｒｉｋｓｅｎ于 1 972年提出本病为线粒体
Leber’s Hereditary Optic Neuropathy (LHON) is a mitochondrial genetic disease that mainly affects the macular fiber and leads to optic neurodegeneration. The disease was first reported by von Graefe (1885), and in 1871 Leber’s collected 55 of 16 families and was identified as an independent genetic disorder. Eriksen proposed in 1972 the disease as mitochondria