癫痫是小儿常见的慢性疾病之一,约25％～30％属于难治性癫痫。难治性癫痫日前尚无统一的诊断标准,通常把多种原因所致的,经正规合理应用传统的抗癫痫药物治疗而未能控制的癫痫视为难治性癫痫。现就引起难治性癫痫的因素及治疗进展综述如下: 1 引起难治性癫痫的主要因素 癫痫的发作类型,发作次数,严重程度,发病年龄,基础疾病,脑电图表现及治疗时机等是难治性癫痫的主要发病因素,惊厥发作频繁,程度严重,持续时间长、 Epilepsy is a common chronic disease in children, about 25% to 30% of refractory epilepsy. Refractory epilepsy there is no uniform diagnostic criteria, usually a variety of reasons, the normal and rational use of traditional antiepileptic drugs and uncontrollable epilepsy as refractory epilepsy. The factors that cause refractory epilepsy and the progress of treatment are summarized as follows: 1 The main factors causing refractory epilepsy Epilepsy type of seizure, the number of seizures, severity, age of onset, underlying diseases, EEG performance and treatment timing is The main risk factors for refractory epilepsy, seizures frequent seizures, the degree of serious, long duration,