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观察98例NIDDM患者彩色多普勒超声心动图、血清胰岛素和C肽释放试验的检测结果,显示在左心室功能障碍的患者血清胰岛素水平、胰岛素/C肽比值均较左心室功能正常的患者增高,而胰岛素敏感性指数则降低,提示高胰岛素血症可能参与NIDDM患者左心室功能异常的发生机制。
The results of color Doppler echocardiography, serum insulin and C peptide release test in 98 cases of NIDDM patients showed that serum insulin and insulin / C peptide ratio of patients with left ventricular dysfunction were higher than those with normal left ventricular function , While the insulin sensitivity index decreased, suggesting that hyperinsulinemia may be involved in the pathogenesis of left ventricular dysfunction in patients with NIDDM.