对30名苯作业人员,其中慢性轻度苯中毒者14名、苯作业观察对象者16名,和60名健康对照者进行了尿、血β_2微球蛋白(β_2-M)测定,结果表明,苯作业人员尿β_2-M 显著高于对照组,且慢性轻度苯中毒组尿β_2-M 高于苯作业观察对象组;血β_2-M 含量在各组间无显著性差异。已知尿β_2-M 能敏感的反映肾小管重吸收功能的变化。故该结果提示,苯作业人员可有肾损害。 The urinary and blood β_2-microglobulin (β_2-M) levels were measured in 30 benzene workers, including 14 chronic mild benzene poisoning patients, 16 benzene target workers and 60 healthy controls. The urinary β_2-M of benzene workers was significantly higher than that of the control group, and the urinary β_2-M of chronic mild benzene poisoning group was higher than that of benzene operation observation group. The blood β_2-M content had no significant difference among the groups. It is known that urinary β_2-M can sensitively reflect the changes of renal tubular reabsorption. Therefore, the results suggest that benzene workers may have kidney damage.