论文部分内容阅读
心内膜心肌纤维化(Endomyocardial Fibrosis,以下简称EMF)是赤道非洲一种地方性流行性疾病,于1948年由Davies在乌干达首先报告该病广泛流行于乌干达、尼日利亚、等热带国家和地区,在欧州及北美仅有个案报告,我国一些省市亦有报告.由于本病的预后差,药物治疗无效,近年来很多作者都建议行手术治疗.病因本病的病因不明,可能与过敏,营养不良、病毒、微丝蚴以及过度摄入富含5-羟色胺的物质有关.近年来多认为与免疫性损伤有关,因为71%的患者发现有抗心抗体,88%有IgG和IgM混合型冷球蛋白,故一些学者指出EMF可能是心脏对链球菌、丝虫病、疟原虫及其它某些毒素或过敏原作用而发生免疫性损伤的结果.
Endomyocardial fibrosis (EMF) is a endemic disease in the equatorial Africa. It was first reported by Davies in Uganda in 1948 that the disease is widely prevalent in Uganda, Nigeria and other tropical countries and regions. In addition, Europe and North America only case reports, some provinces and cities in our country have also reported .Because of the poor prognosis of the disease, drug treatment is invalid, in recent years, many authors suggest surgery .EtiologyThe etiology of the disease is unknown, may be associated with allergies, malnutrition , Viruses, microfilaria, and excessive intake of serotonin-rich substances in recent years, many believe that with the immune damage, because 71% of patients found to have anti-heart antibodies, 88% mixed IgG and IgM cold ball Some scholars have pointed out that EMF may be the heart of streptococci, filariasis, Plasmodium and some other toxins or allergens and the occurrence of immune damage results.