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将糖尿病肾病Ⅲ期患者100例,采用抽签法随机分为观察组50例,对照组50例。两组均采用常规降糖治疗,达到良好的血糖水平。同时配合积极控制血压、调脂治疗。观察组在对照组治疗的基础上加静滴参芎葡萄糖注射液200ml(加优泌林R4u),每天一次,连续14天;对照组不给予上述治疗,但控制血压、血脂、血糖等其它治疗方法两组相似。观察治疗前后尿白蛋白排泄率(UAER)、尿β2-微球蛋白(Uβ2-M G)结果和对照组比较,观察组患者24小时UAER和Uβ2-M G降低(P<0.05)。结论静脉应用参芎葡萄糖注射液治疗糖尿病肾病Ⅲ期疗效良好,短期有减少UAER和Uβ2-M G的作用。
One hundred patients with stage Ⅲ diabetic nephropathy were randomly divided into observation group (n = 50) and control group (n = 50) by random selection method. Both groups were treated with conventional hypoglycemic treatment to achieve good blood sugar levels. At the same time with active control of blood pressure, lipid-lowering treatment. On the basis of the treatment of the control group, the observation group received intravenous infusion of 200ml of gan xue glucose injection (plus gorupine R4u) once daily for 14 days. In the control group, the above treatment was not given, but other treatments such as blood pressure, lipids and blood glucose Methods Two groups were similar. Urinary albumin excretion rate (UAER) and urinary β2-microglobulin (Uβ2-M G) before and after treatment were observed. Compared with the control group, UAER and Uβ2-M G in the observation group decreased 24 hours (P <0.05). Conclusion The application of Shenxiong and glucose injection in the treatment of diabetic nephropathy stage Ⅲ has a good curative effect and short-term effects of reducing UAER and Uβ2-M G.