论文部分内容阅读
目的分析肺炎支原体肺炎(Mycoplasma pneumoniae pneumonia,MPP)患儿发生肺外并发症的危险因素。方法回顾性分析155例MPP患儿的临床资料,统计肺外并发症发生情况,logistic回归分析发生肺外并发症的危险因素。结果 155例MPP患儿中60例发生肺外并发症,占38.71%;单因素分析结果显示,发热持续时间>7d、CRP>5mg/L、肺部实变影、发病7d后应用大环内酯类抗生素与MPP患儿发生肺外并发症有关(P<0.01);多因素logistic回归分析结果显示,肺部实变影(OR=35.22,P=0.000)、C反应蛋白(OR=2.52,P=0.006)、发病7d后应用大环内酯类抗生素(OR=1.77,P=0.015)是发生肺外并发症的危险因素。结论 MPP患儿发生肺外并发症与肺部实变影、C反应蛋白、未及时应用大环内酯类抗生素有关。
Objective To analyze the risk factors of pulmonary complications in children with Mycoplasma pneumoniae pneumonia (MPP). Methods The clinical data of 155 children with MPP were retrospectively analyzed. The incidence of extra-pulmonary complications was analyzed. Logistic regression was used to analyze the risk factors of extra-pulmonary complications. Results Among the 155 MPP cases, 60 cases had extrapulmonary complication, accounting for 38.71%. Univariate analysis showed that the duration of fever> 7 days, CRP> 5 mg / L, pulmonary consolidation, The results of multivariate logistic regression analysis showed that there was no significant difference in the incidence of pulmonary fibrosis (OR = 35.22, P = 0.000), C reactive protein (OR = 2.52, P = 0.006). The use of macrolide antibiotics (OR = 1.77, P = 0.015) after 7 days of onset was a risk factor for pulmonary complications. Conclusions Pulmonary complications in children with MPP are associated with pulmonary consolidation, C-reactive protein and the lack of timely use of macrolide antibiotics.