论文部分内容阅读
目的:探讨MRI弥散张量成像(DTI)显示脑白质纤维束在脑胶质瘤外科的意义。方法:2003年9月至2004年12月,30例脑内肿瘤患者接受术前常规头颅MRI序列检查的同时,进行DTI序列扫描,经后处理得到各向异性分数(FA)图显示脑白质纤维束结构,并进行FA值、图像信号强度及对比度的分析研究。结果:所有病例均成功实现包括DTI序列扫描以及FA图像生成。脑白质纤维束显示为显著的高信号结构;灰质显示为等信号;脑脊液显示为低信号;脑内肿瘤呈类圆形等、低信号灶;肿瘤周围间质水肿区白质纤维束仍能在DTI的FA图上显像。DTI的FA图像对于脑白质纤维束显影的信号对比度明显优于常规的T1W图像。结论:DTI影像可以清晰显示脑白质纤维束的形态结构。结合其他序列的MRI应用于脑胶质瘤的术前诊断,可以准确判别肿瘤和周围脑白质纤维束的毗邻关系,对脑胶质瘤手术方案设计以及术后神经功能障碍的预测与预防具有重要意义。
Objective: To investigate the significance of MRI diffusion tensor imaging (DTI) in the brain glioma surgery. METHODS: From September 2003 to December 2004, 30 patients with intracranial tumors underwent preoperative MRI examinations of the head, and scanned by DTI sequence. The anisotropy fraction (FA) Beam structure, and FA value, image signal intensity and contrast analysis. Results: All cases were successfully completed including DTI sequence scan and FA image generation. Cerebral white matter fiber bundles showed a significant high signal structure; gray matter showed equal signal; cerebrospinal fluid showed low signal; brain tumors were round and so on, low signal focus; tumor around the interstitial edema white matter fiber bundles still in the DTI The FA chart was developed. The signal contrast of DTI FA images for white matter fiber bundle development was significantly better than conventional T1W images. Conclusion: DTI images can clearly show the morphological structure of white matter bundles. Combined with other sequences of MRI applied to the preoperative diagnosis of glioma, can accurately determine the adjacent tumor and the surrounding white matter fiber bundles of brain glioma surgical design and postoperative neurological dysfunction prediction and prevention is important significance.