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目的探讨慢性阻塞性肺疾病(COPD)患病的相关危险因素。方法采用病例对照的研究方法,以291例COPD患者为病例组,同时以来东方市东方医院内科进行健康检查的无COPD的301名人员为对照组,采用单因素和多因素的方法来分析COPD患病的相关危险因素。结果多因素logistic回归分析结果显示年龄(OR=1.052)、呼吸频率(OR=3.193)、居住地周围污染(OR=1.574)、吸烟(OR=5.230)、烟龄(OR=1.965)、反复呼吸道感染(OR=3.777)、呼吸系统疾病家族史(OR=16.035)为COPD患病的危险因素,而人均居住面积(OR=0.592)为COPD患病的保护因素。结论COPD患病的高危因素包括高龄、高呼吸频率、居住地有烟尘或粉尘污染、人均居住面积小、吸烟及烟龄、反复呼吸道感染及呼吸系统疾病家族史等,应针对可改变的高危因素进行综合干预,从而降低人群COPD的患病率。
Objective To explore the related risk factors of COPD. Methods A case-control study was conducted in which 291 patients with COPD were selected as the case group and 301 patients without COPD were enrolled in the study. COPD patients were analyzed by univariate and multivariate analysis Disease-related risk factors. Results The results of multivariate logistic regression analysis showed that age (OR = 1.052), respiratory rate (OR = 3.193), contamination around residence (OR = 1.574), smoking (OR = 3.777), family history of respiratory diseases (OR = 16.035) were the risk factors of COPD, and the per capita living space (OR = 0.592) was the protective factor of COPD. Conclusions High risk factors for COPD include elderly age, high respiratory rate, dust or dust pollution in residence, small living area per person, smoking and cigarette age, recurrent respiratory tract infections and family history of respiratory diseases. The risk factors for COPD For a comprehensive intervention to reduce the prevalence of COPD in the population.