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目的:观察国产西洋参茎叶皂甙(PQS)对肝损伤的保护作用。方法:采用急性乙醇中毒大鼠模型为研究对象。结果:PQS能降低血清过氧化脂质(MDA)、血清谷丙转氨酶(SGPT)、血清谷草转氨酶(SGOT)活性,减少肝脏MDA的生成,增加肝谷胱甘肽过氧化物酶(GSHPx)活性。结论:提示PQS对肝损伤具有保护作用
OBJECTIVE: To observe the protective effect of PQS on hepatic injury. Methods: The acute alcohol intoxication rat model was used as the research object. Results: PQS can reduce serum MDA, SGPT and SGOT activities, reduce the production of MDA in liver and increase the activity of glutathione peroxidase (GSHPx) in liver. . Conclusion: It is suggested that PQS has protective effect on liver injury