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[目的]分析本地区反流性食管炎(RE)的发病情况及临床特征。[方法]收集2011年10月~2014年5月间经胃镜诊断的原发性RE患者786例,按LA分级系统分级,对其一般状况、内镜表现、幽门螺旋杆菌(Hp)感染等资料做回顾性分析。[结果]RE占总胃镜检查人数的2.74%,男女性别比为2.93:1,发病年龄为(50.9±12.5)岁,其中A、B级者90.7%,C、D级者仅9.3%,RE患者Hp阳性率低于受检人群,轻度RE比中、重度的Hp感染率高,RE合并消化性溃疡人群Hp感染率与同期受检人群差异无统计学意义。中重度RE在男性中更容易发生,且合并溃疡的概率更高。[结论]RE患者轻者占大多数,Hp感染可能对RE是一保护因素,中重度RE患者发生消化性溃疡的危险因素与Hp无关。
[Objective] To analyze the incidence and clinical features of reflux esophagitis (RE) in this area. [Methods] A total of 786 primary RE patients diagnosed by gastroscope from October 2011 to May 2014 were collected. The patients were classified according to LA classification system. The general status, endoscopic findings, H. pylori (Hp) infection and other data Do retrospective analysis. [Results] RE accounted for 2.74% of the total number of gastroscopy, the ratio of male to female was 2.93: 1, and the age of onset was (50.9 ± 12.5) years old, of which 90.7% were A and B, 9.3% The positive rate of Hp in patients was lower than that of the subjects, the mild RE was higher than that of moderate and severe H.pylori infection, and there was no significant difference in Hp infection rate between the RE combined with peptic ulcer patients and those in the same period. Moderate to moderate RE is more likely to occur in men and has a higher probability of ulceration. [Conclusion] The majority of patients with RE are light, and Hp infection may be a protective factor for RE. The risk factors for peptic ulcer in patients with moderate and severe RE are not related to Hp.