The Expression of Ezrin and Its Signiifcance in Non-small Cell Lung Cancer

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Objective:To explore the expression of ezrin and its signiifcance in non-small cell lung cancer (NSCLC). Methods:The expression of ezrin in 81 NSCLC patients were examined by immunohistochemical staining Envision method, and its relationships with the clinopathologic features and other indexes were analyzed. Results:The high expression rate of ezrin in NSCLC was 59.26% (48/81) and significantly correlated with lymph node metastasis (P < 0.05), but not associated with gender, histologic subtype, differentiation, TNM stages or smoking. The K-M survival analysis demonstrated that patients with the over-expression of ezrin were obviously poorer than those with low-expression of ezrin (P
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