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目的:考察盐酸多巴胺注射液与单硝酸异山梨酯注射液在葡萄糖注射液中的配伍稳定性。方法:监测盐酸多巴胺注射液与单硝酸异山梨酯注射液配伍后于20、30℃时自然光照射下24h内的含量变化,同时考察配伍液pH值与外观的变化情况。结果:二者配伍后18h内外观、pH值、含量无显著变化。结论:盐酸多巴胺注射液与单硝酸异山梨酯注射液在20、30℃下可配伍用于静脉滴注,但宜在18h内使用完毕。
Objective: To investigate the compatibility of dopamine hydrochloride injection and isosorbide mononitrate injection in glucose injection. Methods: The changes of content of dopamine hydrochloride injection and isosorbide mononitrate injection were observed under natural light irradiation at 20 and 30 ℃, and the changes of pH value and appearance of the compatibility solution were also observed. Results: There was no significant change in appearance, pH and content within 18 hours after compatibility. CONCLUSION: Dopamine hydrochloride injection and isosorbide mononitrate injection can be used as intravenous drip at 20,30 ℃, but it should be used within 18h.