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Ｐ选择素 (Ｐ ｓｅｌｅｃｔｉｎ)作为血小板 /内皮细胞活化分子及粘附受体 ,在早期炎症、血栓形成、肿瘤转移等发挥重要作用[1 5] ,已成为近年研究热点。然而有关Ｐ选择素分子表位结构与其功能关系研究将有助于进一步阐明Ｐ选择素生理、病理意义及其参与疾病发病机制的作用 ,进
P selectin plays an important role in the early stage of inflammation, thrombosis and tumor metastasis as platelet / endothelial cell activation molecules and adhesion receptors [15] and has become a hot topic in recent years. However, the research on the relationship between P-selectin epitope structure and its function will help further clarify the physiological and pathological significance of P-selectin and its role in the pathogenesis of the disease