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Ames 试验是用鼠伤寒沙门氏菌的组氨酸营养缺陷型菌株,在有微粒体酶系统参入活化的条件下,使之发生回复突变的性能来检测化学物质致突变性的一种测试方法,是目前世界上用以筛造化学致癌物较为快速的方法。氯乙烯单体(VCM)是当前全世界应用较广的制造聚氯乙烯塑料的原料,其对人体健康的危害性近二十年来逐渐被人们所认识,1980年国际癌症研究机构工作小组认为是
Ames test is a test method for the detection of mutagenicity of chemical substances using the histidine auxotrophic strain of Salmonella typhimurium under the condition that the microsomal enzyme system is activated, The world’s fastest way to screen chemical carcinogens. Vinyl chloride monomer (VCM) is a widely used raw material for making polyvinyl chloride plastics in the world. Its harmfulness to human health has been gradually recognized for nearly two decades. In 1980, the IOM working group considered that